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 魏雅槟    副研究员



      

北京大学中国药物依赖性研究所

副研究员,博士生导师

联系方式:北京市海淀区学院路38号,邮编100191

Tel: 82802456

Email:yabin.wei@bjmu.edu.cn; yabin.wei@hotmail.com

 

研究方向

  • 抑郁症、双相情感障碍的发病与治疗机制研究
  • 儿童孤独症等神经发育障碍性疾病的发病与治疗机制研究
  • 体外诱导干细胞、3D脑类器官在神经精神疾病中的应用 

教育背景

2005 - 2010   北京大学医学部          医学学士

2011 - 2015   Karolinska Institutet    博士 

研究经历

2016 - 2017   Scripps Research Institute   博士后

2017 - 2019   University of California San Diego   博士后

2020 - 现在   北京大学医学部   副研究员 

代表论文

1Liu JJ*, Huang X*, Bao YP, Lu L, Dong P, Wolkowitz OM, Kelsoe JR, Shi J#, Wei YB#. Painful physical symptoms and antidepressant treatment outcome in depression: a systematic review and meta-analysis. Molecular Psychiatry. 2024 Mar 13.

2Lan K, Wang XX, Lu Y, Zhang A, Jia M, Lu L, Wei YB#, Liu JJ#. Comparison of the Clancy Autism Behavior Scale and Autism Behavior Checklist for Screening Autism Spectrum Disorder. J Autism Dev Disord. 2023 Dec 8.

3Liu JJ*, Wei YB*, Strawbridge R, Bao Y, Chang S, Shi L, Que J, Gadad BS, Trivedi MH, Kelsoe JR, Lu L. Peripheral cytokine levels and response to antidepressant treatment in depression: a systematic review and meta-analysis. Mol Psychiatry. 2019 Aug 19.

4Wei YB, McCarthy M, Ren H, Carrillo-Roa T, Shekhtman T, DeModena A, Liu JJ, Leckband S, Mors O, Rietschel M, Henigsberg N, Cattaneo A, Binder EB, Aitchison KJ, Keloe JR. A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression. Mol Psychiatry. 2019 Mar 15.

5Wei YB, Liu JJ, ?berg E, Brené S, Wegener G, Mathé AA, Lavebratt C. Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression. Transl Psychiatry. 2016 Aug 16;6:e869.

6Wei YB, Melas PA, Villaescusa JC, Liu JJ, Xu N, Christiansen SH, Elbr?nd-Bek H, Woldbye DP, Wegener G, Mathé AA, Lavebratt C. MicroRNA 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter SLC1A1 (EAAT3) in vitro. Int J Neuropsychopharmacol. 2016 Aug 9.

7Wei YB, Martinsson L, Liu JJ, Forsell Y, Schalling M, Backlund L, Lavebratt C. hTERT genetic variation in depression.J Affect Disord. 2015 Sep 16;189:62-69.

8Wei YB, Backlund L, Wegener G, Mathé AA, Lavebratt C.Telomerase dysregulation in the hippocampus of a rat model of depression. Normalization by lithium.Int J Neuropsychopharmacol. 2015 Jan 24.

 

9Wei YB, Melas PA, Wegener G, Mathé AA, Lavebratt C.Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene.Int J Neuropsychopharmacol. 2014 Oct 31;18(2).

 

10)Martinsson L*, Wei YB*, Xu D, Melas PA, Mathé AA, Schalling M, Lavebratt C, Backlund L. Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres. Transl Psychiatry. 2013 May 21; 3:e261.

 

*Shared first authorship.

#Shared correspondence.