电话:13261995331或010-82802456
传真:010-62032624
E-mail:yinghan@bjmu.edu.cn
简介
医学博士,博士生导师,北京大学中国药物依赖性研究所研究员,教育部青年长江学者,北大博雅青年学者,北医青年学者,入选中国科协青年人才托举工程。长期从事抑郁症等应激相关精神障碍的神经机制和干预策略研究,作为第一/通讯(含共同)作者在Science Bulletin、Science Advances、Molecular Psychiatry、Sleep Medicine Reviews和Brain Behavior and Immunity等期刊发表SCI论文39篇,4篇入选ESI高被引文章,1篇被F1000推荐,申请发明专利9项并获得授权5项,获2022年中华医学科技奖二等奖、2022年首都前沿学术成果、CINP 2024 Excellent Presentation Award等学术奖励。担任中国心理学会生理心理专业委员会委员、中华医学会精神病学分会焦虑障碍研究协作组委员、中国毒理学会药物依赖性专业委员会委员、中国毒理学会青年委员会委员、北京神经科学学会青年工作委员会委员、Brain Behavior and Immunity Integrative编委、Stress and Brain青年编委等,主持国家重点研发计划课题、国自然青年和面上项目、脑计划青年项目任务等。
主要研究方向
1)应激导致精神行为异常的差异化分子和神经环路机制及其上下游精细结构和功能特征解析
2)中枢-外周调控的神经环路机制及其在精神疾病共病躯体疾病中的应用
3)精神疾病共病的微生物-肠-脑轴机制及特定细菌菌株/代谢物的作用
代表性论著
1. Wang Zhe#, Wang Zhong#, Lu Tangsheng#, Yuan Guohao#, Chen Wenhao, Jin Jin, Jiang Xianhong, Yan Wei, Yuan Kai, Zou Guichang, Bao Yanping, Shi Jie, Liu Xiaoxing*, Wei Hong*, Han Ying*, Lu Lin*. Gut microbiota regulate insomnia-like behaviors via gut-brain metabolic axis. Mol Psychiatry. 2024 In press.
2. Yao Yuan#, Guo Dan#, Lu Tang-Sheng#, Liu Fang-Lin, Huang Shi-Hao, Diao Meng-Qi, Li Su-Xia, Zhang Xiu-Jun, Kosten Thomas R, Shi Jie, Bao Yan-Ping*, Lu Lin*, Han Ying*. Efficacy and safety of psychedelics for the treatment of mental disorders: A systematic review and meta-analysis. Psychiatry Res. 2024 Mar 28:335:115886.
3. Liu Xiaoxing#, Lu Tangsheng#, Chen Xuan, Huang Shihao, Zheng Wei, Zhang Wen, Meng Shiqiu, Yan Wei, Shi Le, Bao Yanping, Xue Yanxue*, Shi Jie, Yuan Kai, Han Ying*, Lu Lin*. Memory consolidation drives the enhancement of remote cocaine memory via prefrontal circuit. Mol Psychiatry. 2024 Mar;29(3):730-741.
4. Chen Wenjun#, Zhang Yan#, Liang Jie#, Zhang Zhongyu, Zhang Libo, Huang Enze, Zhang Guipeng, Lu Lin*, Han Ying*, Shi Jie*. Disrupting astrocyte-neuron lactate transport prevents cocaine seeking after prolonged withdrawal. Sci Adv. 2023 Oct 27;9(43):eadi4462.
5. Lu Tangsheng#, Liu Xiaoxing#, Sun Jie, Bao Yanping, Bj?rn W Schuller, Han Ying*, Lu Lin*. Bridging the gap between artificial intelligence and mental health. Sci Bull. 2023 Aug 15;68(15):1606-1610.
6. Yu Zhoulong, Chen Wenjun, Zhang Libo, Chen Yun, Chen Wenxi, Meng Shiqiu, Lu Lin, Han Ying*, Shi Jie*. Gut-derived bacterial LPS attenuates incubation of methamphetamine craving via modulating microglia. Brain Behav Immun. 2023 Mar 31;111:101-115.
7. Liu Xiaoxing#, Yuan Kai#, Lu Tangsheng#, Lin Xiao, Zheng Wei, Xue Yanxue, Shi Jie, Lu Lin*, Han Ying*. Preventing incubation of drug craving to treat drug relapse: from bench to bedside. Mol Psychiatry. 2023 Apr;28(4):1415-1429.
8. Wang Zhe, Wang Zhong, Lu Tangsheng, Chen Wenhao, Yan Wei, Yuan Kai, Shi Le, Liu Xiaoxing, Zhou Xinyu, Shi Jie, Vitiello Michael V., Han Ying*, Lu Lin*. The microbiota-gut-brain axis in sleep disorders. Sleep Med Rev. 2022 Aug 31;65:101691.
9. Yu Zhoulong#, Han Ying#, Hu Die#, Chen Na, Zhang Zhongyu, Chen Wenxi, Xue Yanxue, Meng Shiqiu, Lu Lin, Zhang Wen*, Shi Jie*. Neurocan regulates vulnerability to stress and the anti-depressant effect of ketamine in adolescent rats. Mol Psychiatry. 2022 May;27(5):2522-2532.
10. Wang Zhong#, Chen Wenhao#, Li Suxia, He Zhongming, Zhu Weili, Ji Yanbin, Wang Zhe, Zhu Ximei, Yuan Kai, Bao Yanping, Shi Le, Meng Shiqiu, Xue Yanxue, Xie Wen, Shi Jie, Yan Wei*, Wei Hong*, Lu Lin*, Han Ying*. Gut microbiota modulates the inflammatory response and cognitive impairment induced by sleep deprivation. Mol Psychiatry. 2021 Nov;26(11):6277-6292.
11. Han Ying#, Sun Chengyu#, Meng Shiqiu#, Tabarak Serik, Yuan Kai, Cao Lu, Yan Wei, Xu Lingzhi, Deng Jiahui, Zhu Weili, Li Jiali, Lu Lin*, Xue Yanxue*, Shi Jie*. Systemic immunization with altered myelin basic protein peptide produces sustained antidepressant-like effects. Mol Psychiatry. 2020 Jun;25(6):1260-1274.