Publications of Cochrane Drugs and Alcohol Group and interventions still not considered in the reviews with respective published trials

 

N.B. Reviews = [R]; Protocols of Reviews = [P]; Titles registered = [T]

 

Alcohol abuse and dependence: published reviews, protocols and registered titles

[R] Opioid antagonists for alcohol dependence

[R] Primary Prevention for alcohol misuse in young people

[R] Anticonvulsants for the management of alcohol withdrawal

[R] Benzodiazepines for alcohol withdrawal

[P] Acamprosate for alcohol dependence

[R] Anticonvulsants for alcohol withdrawal

[R] Benzodiazepines for alcohol withdrawal

[P] Psychosocial interventions for alcohol use disorders

[P] Brief interventions for excessive drinkers in primary care health settings

[P] Acamprosate for alcohol dependence

[P] Disulfiram for alcohol dependence

[P] 12-step type programmes and Alcoholic Anonymous for alcohol dependence

[P] Psychotropic analgesic nitrous oxide for alcoholic withdrawal states

[P] Brief interventions for heavy alcohol users in general medical wards

[P] Selective serotonin reuptake inhibitors for alcohol use disorders

[P] Disulfiram for alcohol dependence

[T] Strategies and interventions for infants, children and youth exposed to alcohol in utero aimed at mitigating morbidities and secondary disabilities in children and youth affected with foetal alcohol spectrum disorder.  

[T] Psychological interventions for family members of alcohol misusers

[T] Gamma-Hydroxybutyrate (GBH) for alcohol withdrawal

[T] Acupuncture for alcohol dependence

[T] Antidepressants for depressed patients with co-morbid alcohol dependence

[T] Managed Alcohol as a Harm Reduction Intervention for Alcohol Addiction in Populations at [T] High Risk for Substance Abuse

[T] Social norms interventions for the prevention of alcohol misuse in young people

 

Alcohol abuse and dependence: pharmacological interventions for which new reviews should be developed and relative published trial identified with a preliminary literature search.

Antipsychotic               (45)

Antibiotic                     (17)

Beta blockers               (14)

Anti nausea                  (12)

Antihypertensive          (11)

Sedative, Anxiolytic, Hypnotic (13)

Antidepressant             (9)

Hallucinogen                (8)

Psychostimulant            (7)

Antioxidant                  (6)

Alcohol antagonist            (4)

Antispasmodic            (4)

Anti Parkinson            (3)

Calcium channel blockers (3)

Interferon                     (2)

Plant                            (2)

Aspartate antagonist            (1)

Furthermore we found 21 trials that compared different settings

 

 

Cocaine and other psychostimulants abuse and dependence: published reviews, protocols and registered titles

[R] Carbamazepine for cocaine dependence

[R] Dopamine agonists for cocaine dependence

[R] Antidepressants for cocaine dependence

[R] Auricular acupuncture for cocaine dependence

[T]Antipsychotic for cocaine dependence

[R] Treatment for amphetamine dependence and abuse

[R] Treatment for amphetamine psychosis

[R] Treatment for amphetamine withdrawal

Psychosocial interventions

[P] Psychosocial treatments for psychostimulants dependence

 

Cocaine and other psychostimulants abuse and dependence:  pharmacological interventions for which new reviews should be developed and relative published trial identified with a brief literature search.

Psychostimulant            (18)

Anticonvulsant            (16)

Antihypertensive          (11)

Anorexigenic                (8)

Alcohol antagonist            (7)

Anti Parkinson            (7)

Opioid antagonist            (7)

Aminoacid                   (5)

Antispasmodic            (3)

Mucolytic agent            (2)

Pain killer                     (2)

Furthermore we found 7 trials that compared different settings

 

Polydrug: published reviews, protocols and registered titles

 [R] Interventions for prevention of drug use by young people delivered in non-school settings

[R] School-based prevention for illicit drugs' use

[P] Parenting programmes for preventing tobacco, alcohol or drugs abuse in children under 18

[R] Therapeutic communities for substance related disorder

[P] Psychosocial interventions for pregnant women in outpatient illicit drug treatment programs

[P] Interventions for drug-using offenders in the courts, secure establishments and the community.

[T] Compulsory treatment compared to voluntary treatment for users of illegal drugs

[T] Case management for substance use disorders

 

Polydrug: interventions for which new reviews should be developed and relative published trial identified with a brief literature search.

Pharmacological interventions             (7)

Psychosocial interventions                 (18)

 

 

 

Other uncovered areas:

Hallucinogens abuse and dependence; Inhalants

 

 

Opiate abuse and dependence: published reviews, protocols and registered titles

 

[R] Oral naltrexone maintenance treatment for opioid dependence

[R] Opioid antagonists with minimal sedation for opioid withdrawal

[R] Buprenorphine for the management of opioid withdrawal

[R] Alpha2 adrenergic agonists for the management of opioid withdrawal 

[R] Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal

[R] Methadone at tapered dosages for the management of opioid withdrawal

[R] LAAM maintenance versus methadone maintenance for heroin dependence

[R] Methadone maintenance versus no opioid replacement therapy for opioid dependence

[R] Buprenorphine maintenance versus methadone maintenance for opioid dependence

[R] Methadone maintenance at different dosages for heroin dependence

[R] Heroin maintenance for chronic heroin dependents

[R] Substitution treatment for injecting opioid users for prevention HIV infection

[R] Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence

[R] Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification

[R] Psychosocial treatments for opiate abuse and dependence

[R] Treatment for Methaqualone dependence in adults

[R] Inpatient versus other settings for detoxification for opioid dependence

[P] Neuroelectric stimulation for the management of opioid withdrawal

[P] Acupuncture for opioid dependence

[P] Traditional Chinese medicine for opioid withdrawal syndrome

[T] Maintenance treatment for opiate dependent adolescents

[T] Maintenance treatment for opiate dependent pregnant women

[T] Detoxification treatment for opiate dependent adolescents

 

The opiate dependence and abuse is the most covered area and probably it is not a priority to develop new reviews on this topic.

 

Other: published reviews, protocols and registered titles

Cannabis abuse and dependence

 [P] Psychotherapeutic interventions for cannabis abuse and/or dependence in outpatient settings

Iatrogenic use of prescribed drugs

 [P] Pharmacological interventions for benzodiazepine dependence management among benzodiazepine users in outpatient settings

Other drugs

[R] Treatment for Methaqualone dependence in adults